.skip-link { position: absolute; top: -40px; left: 0; background: #0A4D68; color: #fff; padding: 8px 16px; z-index: 9999; font-size: 14px; border-radius: 0 0 4px 0; transition: top .2s; text-decoration: none; }
        .skip-link:focus { top: 0; }
        :root {
            --primary: #0A4D68; --primary-dark: #06384d; --accent: #047857; --secondary: #D97706;
            --bg-body: #FAFAF9; --bg-card: #FFFFFF; --text-main: #1C1917; --text-muted: #57534E;
            --border-subtle: #E7E5E4; --container-width: 1200px; --header-height: 90px;
        }
        [data-theme="dark"] { --bg-body: #0C0A09; --bg-card: #1C1917; --text-main: #F5F5F4; --text-muted: #A8A29E; --primary: #38BDF8; --accent: #34D399; --border-subtle: #292524; }
        * { margin: 0; padding: 0; box-sizing: border-box; }
        body { font-family: 'Source Sans 3', sans-serif; background-color: var(--bg-body); color: var(--text-main); line-height: 1.7; -webkit-font-smoothing: antialiased; transition: background-color 0.5s ease, color 0.5s ease; }
        h1, h2, h3, h4, h5, h6 { font-family: 'Playfair Display', serif; font-weight: 700; color: var(--primary); letter-spacing: -0.02em; }
        a { text-decoration: none; color: inherit; transition: 0.3s ease; }
        ul { list-style: none; }
        img { max-width: 100%; display: block; }
        @keyframes fadeInUp { from { opacity: 0; transform: translateY(20px); } to { opacity: 1; transform: translateY(0); } }
        @keyframes rotate-scale { 0% { transform: rotate(0) scale(1); } 50% { transform: rotate(180deg) scale(1.2); } 100% { transform: rotate(360deg) scale(1); } }
        .animate-fade-in { animation: fadeInUp 0.8s ease-out forwards; }
        .animate-theme-switch i, .animate-theme-switch svg { animation: rotate-scale 0.5s ease-in-out; }
        .container { max-width: var(--container-width); margin: 0 auto; padding: 0 24px; }
        .top-bar { background-color: #0A4D68; color: #fff; padding: 8px 0; font-size: 0.85rem; position: relative; z-index: 1002; }
        .top-bar .container { display: flex; justify-content: flex-end; gap: 20px; padding-right: 20px; }
        .lang-selector { display: flex; align-items: center; gap: 5px; }
        .lang-selector select { background: transparent; color: #fff; border: none; font-size: 0.85rem; cursor: pointer; outline: none; }
        .lang-selector select option { color: #000; }
        .main-header { background-color: var(--bg-card); border-bottom: 1px solid var(--border-subtle); width: 100%; z-index: 1000; height: var(--header-height); position: sticky; top: 0; }
        .main-header .container { display: flex; justify-content: space-between; align-items: center; height: 100%; padding-left: 40px; padding-right: 40px; }
        .logo { font-family: 'Playfair Display', serif; font-size: 2rem; font-weight: 700; color: var(--primary); display: flex; align-items: center; gap: 12px; letter-spacing: -0.03em; }
        .nav-menu { display: flex; gap: 32px; }
        .nav-link { font-family: 'Source Sans 3', sans-serif; font-weight: 600; color: var(--text-muted); font-size: 1rem; text-transform: uppercase; letter-spacing: 0.05em; position: relative; }
        .nav-link::after { content: ''; position: absolute; width: 0; height: 2px; bottom: -4px; left: 0; background-color: var(--secondary); transition: width 0.3s; }
        .nav-link:hover::after { width: 100%; }
        .nav-link:hover { color: var(--primary); }
        .btn-outline-white { border: 1px solid var(--primary); color: var(--primary); padding: 8px 24px; border-radius: 2px; text-transform: uppercase; font-size: 0.85rem; font-weight: 600; letter-spacing: 0.05em; }
        .btn-outline-white:hover { background-color: var(--primary); color: #fff; }
        .article-hero { background: linear-gradient(135deg, var(--primary) 0%, var(--primary-dark) 100%); color: #fff; padding: 80px 0; min-height: 350px; display: flex; align-items: center; }
        .article-hero-content { max-width: 800px; padding-left: 20px; }
        .article-tag { background-color: var(--secondary); color: #fff; padding: 4px 12px; text-transform: uppercase; font-size: 0.75rem; font-weight: 700; letter-spacing: 0.1em; border-radius: 2px; display: inline-block; margin-bottom: 20px; }
        .article-hero h1 { font-size: 3.5rem; color: #fff; line-height: 1.1; margin-bottom: 20px; }
        .article-meta { display: flex; align-items: center; gap: 20px; font-size: 0.9rem; color: rgba(255,255,255,0.8); font-family: 'Source Sans 3', sans-serif; margin-top: 30px; }
        .meta-item { display: flex; align-items: center; gap: 8px; }
        .article-container { max-width: 900px; margin: 60px auto; padding: 0 24px; display: block; }
        .article-body { font-size: 1.2rem; color: var(--text-main); line-height: 1.85; }
        .article-body p { margin-bottom: 1.8em; text-align: justify; }
        .article-body h2 { font-size: 2.2rem; margin-top: 2.5em; margin-bottom: 0.8em; color: var(--primary); text-align: center; border-bottom: 2px solid var(--accent); padding-bottom: 10px; display: inline-block; width: 100%; }
        .article-body h3 { font-size: 1.6rem; margin-top: 2.2em; margin-bottom: 0.8em; color: var(--text-main); font-family: 'Playfair Display', serif; font-weight: 700; }
        .article-body ul, .article-body ol { margin-bottom: 2em; padding-left: 20px; max-width: 90%; margin-left: auto; margin-right: auto; }
        .article-body li { margin-bottom: 0.8em; padding-left: 10px; position: relative; }
        .article-body ul li::marker { color: var(--accent); }
        .article-body strong { color: var(--primary); font-weight: 700; }
        .clinical-pearl { background-color: rgba(4, 120, 87, 0.05); border-left: 4px solid var(--accent); padding: 30px; margin: 50px auto; border-radius: 4px; box-shadow: 0 4px 20px rgba(0,0,0,0.03); }
        .clinical-pearl h4 { color: var(--accent); font-family: 'Source Sans 3', sans-serif; text-transform: uppercase; font-size: 0.85rem; letter-spacing: 0.1em; margin-bottom: 10px; display: flex; align-items: center; gap: 8px; }
        [data-theme="dark"] .clinical-pearl { background-color: rgba(4, 120, 87, 0.15); }
        .scientific-quote { font-family: 'Playfair Display', serif; font-style: italic; font-size: 1.5rem; color: var(--text-muted); text-align: center; margin: 50px 0; padding: 0 40px; position: relative; }
        .scientific-quote::before { content: '\201C'; font-size: 4rem; color: var(--secondary); opacity: 0.3; display: block; line-height: 0.5; margin-bottom: 20px; }
        .scientific-table { width: 100%; border-collapse: collapse; margin: 50px 0; font-size: 0.95rem; box-shadow: 0 10px 30px rgba(0,0,0,0.05); border-radius: 6px; overflow: hidden; }
        .scientific-table th { background-color: var(--primary); color: #fff; padding: 18px; text-align: left; font-family: 'Source Sans 3', sans-serif; font-weight: 600; letter-spacing: 0.05em; }
        .scientific-table td { border-bottom: 1px solid var(--border-subtle); padding: 18px; vertical-align: top; }
        .scientific-table tr:nth-child(even) { background-color: rgba(0,0,0,0.02); }
        [data-theme="dark"] .scientific-table tr:nth-child(even) { background-color: rgba(255,255,255,0.02); }
        .references-section { margin-top: 100px; padding-top: 60px; border-top: 1px solid var(--border-subtle); font-size: 0.9rem; color: var(--text-muted); }
        .references-section h3 { margin-top: 0; font-size: 1.5rem; margin-bottom: 30px; text-align: left; }
        .ref-item { margin-bottom: 15px; word-break: break-word; padding-left: 20px; text-indent: -20px; }
        .toc-integrated { background-color: var(--bg-body); border: 1px solid var(--border-subtle); border-top: 4px solid var(--secondary); padding: 30px; margin-bottom: 60px; border-radius: 4px; }
        .toc-title { font-family: 'Playfair Display', serif; font-size: 1.3rem; margin-bottom: 20px; color: var(--text-main); font-weight: 700; text-align: center; }
        .toc-list { display: grid; grid-template-columns: 1fr 1fr; gap: 10px 30px; padding: 0; }
        .toc-list li { list-style: none; margin: 0; font-size: 0.95rem; }
        .toc-list a { color: var(--primary); text-decoration: none; border-bottom: 1px dotted transparent; transition: all 0.2s; }
        .toc-list a:hover { color: var(--accent); border-bottom-color: var(--accent); }
        footer { background-color: #1C1917; color: #A8A29E; padding: 80px 0 0; font-size: 0.95rem; font-family: 'Source Sans 3', sans-serif; border-top: 4px solid var(--accent); margin-top: 100px; }
        .footer-grid { display: grid; grid-template-columns: repeat(auto-fit, minmax(220px, 1fr)); gap: 50px; padding-bottom: 60px; }
        footer h4 { color: #fff; font-family: 'Playfair Display', serif; font-size: 1.3rem; margin-bottom: 25px; letter-spacing: 0.05em; position: relative; }
        footer h4::after { content: ''; display: block; width: 30px; height: 2px; background-color: var(--accent); margin-top: 10px; }
        footer ul li { margin-bottom: 12px; }
        footer ul li a { color: #A8A29E; transition: 0.2s; display: inline-block; }
        footer ul li a:hover { color: #fff; transform: translateX(5px); }
        .footer-bottom { border-top: 1px solid #333; padding: 30px 0; text-align: center; font-size: 0.85rem; background-color: #151312; }
        @media (max-width: 900px) { .nav-menu { display: flex; flex-wrap: wrap; gap: 10px; justify-content: center; } .article-hero h1 { font-size: 2.2rem; } .article-container { padding: 0 20px; } .toc-list { grid-template-columns: 1fr; } .main-header .container { padding-left: 20px; } }